Sökning: "tumor angiogenesis"

Visar resultat 1 - 5 av 14 uppsatser innehållade orden tumor angiogenesis.

  1. 1. Digital Image Analysis using Qupath to determine immune cell content in formalin-fixed, paraffin-embedded murine neuroblastoma tumors

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Anton Bergström Holm; [2023]
    Nyckelord :Neuroblastoma; Tumor-associated neutrophils TANs ; Digital image analysis; QuPath;

    Sammanfattning : Neuroblastoma (NB), an extracranical solid tumor, is among the most prevalent cancers affecting children, particularly those under the age of five. High-risk NB presents a survival rate just below 50 %. Angiogenesis, a crucial process in NB, is induced by various pro-angiogenic factors. LÄS MER

  3. 2. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Maja Hammarström; [2022]
    Nyckelord :neuroblastoma; tumor angiogenesis; sunitinib; SU11248; tumor-associated neutrophils; immunohistochemistry;

    Sammanfattning : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. LÄS MER

  4. 3. The effect of deactivation or silencing of tumor stroma with angiogenesis inhibitor on malignancy of tumor metastases

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Nataly Tachijian; [2021]
    Nyckelord :neuroblastoma; SU11248; angiogenesis; tumor-associated macrophages; immunohistochemistry;

    Sammanfattning : Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The survival rate is only around 50 percent for high-risk NB despite advanced and intense multi-modal therapy. Current research aims to find new effective treatment additional to modern therapy to improve prognosis of high-risk NB in children. LÄS MER

  5. 4. Mathematical modelling andsimulation for tumour growth andangiogenesis

    Master-uppsats, Karlstads universitet/Institutionen för matematik och datavetenskap (from 2013)

    Författare :René Edgardo Luna; [2021]
    Nyckelord :Multiscale modelling; tumor growth; angiogenesis; agent-based model; variance reduction;

    Sammanfattning : Cancer is a complex illness that affects millions of people every year. Amongst the most frequently encountered variants of this illness are solid tumours. The growth of solid tumours depends on a large number of factors such as oxygen concentration, cell reproduction, cell movement, cell death, and vascular environment. LÄS MER

  7. 5. Tumör-associerade makrofagers inverkan vid juvertumörer hos hund

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Martin Kläschen; [2019]
    Nyckelord :tumör-associerade makrofager; TAM; makrofager; juvertumör; CMT; hund;

    Sammanfattning : Tumör-associerade makrofager (TAM) är makrofager som under påverkan av tumörceller polariseras mot ett stadie där de frisätter tillväxtfaktorer, cytokiner, kemokiner och enzymer som främjar tumörtillväxt, kärlnybildning, invasion och metastasering. Det har konstaterats att ett högre antal TAM i juvervävnad på hund är associerat med en sämre prognos jämfört med hundar med ett lägre antal TAM. LÄS MER