Sökning: "tumor microenvironment"
Visar resultat 1 - 5 av 13 uppsatser innehållade orden tumor microenvironment.
1. Development and testing of in-house automatized spatial omics data analysis tool : NIPMAP (Niche-Phenotype Mapping)
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : The functional and anatomical characteristics of cancer cells vary among patients. Additionally, therapeutic approaches display varying responses in different individuals and cancer types due to the anatomical and functional complexity of tumor. LÄS MER
2. Comparison of deep learning and model-based approaches for spatial profiling of the immune tumor environment on multiplex image data
Master-uppsats, Uppsala universitet/Institutionen för informationsteknologiSammanfattning : The demographics of the tumor microenvironment (TME) impact the Immunotherapy responses for lung cancer patients. Given the heterogeneity of immune cells present within TME, the distribution patterns of different subpopulations of T-cells can be exploited to predict short-term or long-term survival of lung cancer patients. LÄS MER
3. A comparison between two computational tools estimating tumor purity using NGS data
Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologiSammanfattning : In 2020, cancer accounted for almost 20% of all deaths in the United States. Cancer is highly individual, and individualized treatments are essential in the battle against the disease. The tumor microenvironment is complex, and the cancer genome contains mutations driving the cancer. LÄS MER
4. Characterization of the immunomicroenvironment of glioblastoma : Optimization of an antibody panel for detection of glioblastoma TME cells and effect of C3 on glioma cells.
Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)Sammanfattning : Glioblastoma (GBM) is the most common primary brain tumor in adults and represents one of the most aggressive tumor types. Despite treatment GBM remains incurable and when treated the tumor recurs more aggressive and treatment resistant than before. LÄS MER
5. Hypoxia-induced expression of HIF-1a and GPR30, in relation to survival, proliferation and apoptosis in MCF-7 and SkBr3 breast cancer cells.
L3-uppsats, Lunds universitet/LäkarutbildningenSammanfattning : Introduction: Hypoxia that accompanies tumor growth induces the expression of hypoxiainducible factor a (HIF-1a), in turn mediating the expression of other genes, including G protein-coupled receptor 30 (GPR30), to promote adaption to the hypoxic microenvironment and enable cell proliferation and survival. Nonetheless, this correlation has not been causally explained. LÄS MER
