Sökning: "vascular smooth muscle cell"

Hittade 5 uppsatser innehållade orden vascular smooth muscle cell.

  1. 1. Novel mRNA therapeutics for cardiomyogenesis and vasculogenesis

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Xiaoting Huang; [2022]
    Nyckelord :Heart; Placental growth factor PLGF ; Cardiomyogenesis; Vasculognesis; Regeneration; hjärta; PLGF; kardiomyogenes; vaskulogenes; regenerering;

    Sammanfattning : Kardiovaskulära sjukdomar är fortfarande en av de främsta dödsorsakerna i dag. Den främsta orsaken till sjukdomen är skador på hjärtcellerna, som kanske inte kan repareras av sig själva, så att utveckla en ny terapi för att regenerera eller reparera hjärtcellerna är ett viktigt mål inom forskningen om hjärtsjukdomar. LÄS MER

  3. 2. IL-17A induced response and synergy with otherproinflammatory cytokines in human endothelial cells

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Julia Salin; [2021]
    Nyckelord :cDNA; complementary DNA CVD; cardiovascular disease CXCL1; C-X-C motif ligand-1 EC; endothelial cell ELISA; Enzyme-Linked Immunosorbent Assay HUVECs; human umbilical cord endothelial cells sIL-6R; soluble interleukin 6 receptor IL; interleukin NF-𝜅B; nuclear factor 𝜅B qPCR; quantitative polymerase chain reaction TNF; tumour necrosis factor VSMC; vascular smooth muscle cell;

    Sammanfattning : Cardiovascular diseases are a broad group of diseases, such as heart attack and heart failureaffecting the cardiovascular system. The primary cause of cardiovascular diseases isatherosclerosis, and its progression is brought about by oxidative stress and a complex chronicinflammation reaction cascade. LÄS MER

  4. 3. Fabrication and characterisation of a 3-layer aorta-on-a-chip

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrosystemteknik

    Författare :Karolina Svensson; [2017]
    Nyckelord :Organ-on-a-chip; aorta-on-a-chip; PDMS; COC; microfabrication; APTES;

    Sammanfattning : Endothelial cells, EC, are the cell type closest to the blood stream in vessel walls. These cells can affect the origin of atherosclerosis, plaques clogging the vessels. The behaviour of EC is affected by neighbouring smooth muscle cells and shear stress from the blood flow. LÄS MER

  5. 4. Biomechanics of Arterial Smooth Muscle. : - Analyzing vascular adaptation of large elastic arteries using in vitro experiments and 3D finite element modeling.

    Magister-uppsats, KTH/Hållfasthetslära (Inst.)

    Författare :Susanne Lewin; [2014]
    Nyckelord :;

    Sammanfattning : A number of cardiovascular diseases (e.g. aortic aneurysm, aortic dissection and atherosclerosis) are associated with altered biomechanical properties in the vascular wall. This thesis studies vascular adaptation and its resulting alteration in biomechanical properties. LÄS MER

  7. 5. Impact of Oxygen-Release Material on Human Urine-Derived Stem Cells’ Differentiation and Proliferation in Hypoxic Condition In Vitro

    Uppsats för yrkesexamina på avancerad nivå, Tillämpad materialvetenskap

    Författare :Marie-Louise Krieg; [2010]
    Nyckelord :urine-derived stem cells; hypoxia; VEGF; HIF-1alpha; oxygen release material;

    Sammanfattning : One of today’s most widely spread health problems is urinary incontinence, affecting 60-80% of the US population from age 15 and up. Treatment based on the possibility to implant a scaffold seeded with the patients’ own urine-derived stem cells, hUSC, to regenerate the damaged muscle tissue, would prove effective. LÄS MER