Sökning: "vesicle"

Visar resultat 1 - 5 av 16 uppsatser innehållade ordet vesicle.

  1. 1. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Farhana Manzoor; [2020]
    Nyckelord :Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

    Sammanfattning : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. LÄS MER

  2. 2. Exosomes and lipid nanoparticles - the future of targeted drug delivery

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Sara Lundberg; Emelia Karlsson; Hugo Dahlberg; Mathilda Glansk; Sara Larsson; Sofia Larsson; Karl Carlsson; [2020]
    Nyckelord :Exosomes; lipid nanoparticles; drug delivery;

    Sammanfattning : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. LÄS MER

  3. 3. Patterning of the neural tube: A 3D computational modelling approach

    Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik; Lunds universitet/Beräkningsbiologi och biologisk fysik

    Författare :Ariane Ernst; [2019]
    Nyckelord :gene regulatory networks; neural tube patterning; patterning of the neural tube; dopaminergic neurons; parkinson s disease; computational modelling; stem cell; GRN; Biology and Life Sciences; Physics and Astronomy;

    Sammanfattning : Neurodegenerative diseases such as Parkinson’s can be treated with stem-cell derived specialized neurons. In order to achieve precise directed neural differentiation in vitro we need to understand the gene regulatory mechanisms behind in vivo neural tube patterning. LÄS MER

  4. 4. Affinity of Alpha-Synuclein and Lipid Vesicle Interaction

    Master-uppsats, Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Författare :Ahmed Masaada; [2019]
    Nyckelord :Physics and Astronomy;

    Sammanfattning : Alpha-synuclein is a protein involved in several neurodegenerative diseases, such as Parkinson’s, where it has been observed to form amyloid fibrils or Lewy bodies. However, how or to what extent alpha-synuclein is involved is not known. LÄS MER

  5. 5. Synovial fluid components as synergistic lubricants in articular joint models

    Master-uppsats, KTH/Kemi

    Författare :Sixuan Li; [2019]
    Nyckelord :synergistic lubrication; synovial fluid; biolubrication; DPPC; hyaluronic acid; Mini-Traction Machine; macro- and microscale; profilometer;

    Sammanfattning : The excellent lubrication present within mammalian synovial joints attracted scientific interest, and some close-to-realistic models were applied to study the mechanism in vitro. In this project, the synergistic lubrication of synovial fluid was investigated by using 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), hyaluronic acid (HA), and phosphate-buffered saline (PBS buffer) to mimic the synovial fluid. LÄS MER