INFLAMMATORY BOWEL DISEASE AND IRRITABLE BOWEL SYNDROME IN ADULT LIFE AFTER EXPERIENCING CHILDHOOD ABUSE

Detta är en Kandidat-uppsats från Örebro universitet/Institutionen för medicinska vetenskaper

Författare: Myella Cederholm; [2021]

Nyckelord: ;

Sammanfattning: Introduction In a national survey from 2016, 5% of Swedish teenagers reported experience of repeated physical abuse and 6% reported repeated psychological abuse. Childhood abuse has been shown to enhance the risk of both psychiatric and somatic diseases, e.g. Irritable bowel syndrome (IBS) and also general inflammation. One type of inflammatory disease is inflammatory bowel disease (IBD), which is composed of Ulcerative colitis (UC) and Chron’s disease (CD), but there is limited scientific evidence regarding the correlation of IBD and child abuse. Objective The aim of this systematic review is to study the correlation between childhood abuse and IBD in adulthood and compare this to the correlation of child abuse and IBS. Method PubMed and Web of Science databases were searched for articles studying childhood maltreatment and adult IBS or IBD. Articles that were not peer reviewed and presented original data or did not study IBD patients were excluded. Results 342 articles were identified, of which nine met the pre-defined criteria and were included in this review. Eight articles studied the frequency of childhood abuse among IBS and IBD patients and one article studied disease activity in IBD patients that experienced childhood abuse. Childhood abuse was found to be more frequent in both IBS and IBD patients than healthy controls (HC). CD patients that were abused in childhood had elevated disease activity. Conclusions Childhood physical abuse was associated with both IBD and IBS. Childhood sexual abuse was associated with IBD, but a stronger association was found with IBS. No conclusions could be drawn regarding childhood psychological abuse.

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