LEAN-baserad processoptimering av parental nutritionstillverkning : En teoretisk optimering

Sammanfattning: Fresenius Kabi is a company specializing in clinical nutrition, infusion therapy and medicinal technology. Fresenius Kabi has two production facilities in Sweden, one in Brunna and one in Uppsala. The production facility in Brunna supplies the facility in Uppsala with the raw materials needed to create ampules of anesthetics, bags of parental nutrition, vitamin solutions and many other medicinal products. Fresenius Kabi has recently made a big investment in a software program called PAS-X which is designed to store and control the flow of information during production of the company’s various products. This information is currently written by hand on paper in batch protocols and stored for up to 10 years as part of the company’s quality assurance. The problem with PAS-X and the motivation behind this thesis project is that the production and production information therein is not optimized to be controlled electronically. The production layout and processflow have been largely adapted with manual information storage in mind, making a direct transition to electronic storage problematic. This project was ordered by the PAS-X project group at Fresenius Kabi where the goals were to analyze the production layout and production flow and subsequently rearrange the production layout and revise the process using a LEAN methodology. By identifying and eliminating areas of waste and also standardizing the production of one of the company’s main products, SMOFKabiven, this thesis and the work behind it was able to theoretically reduce transportation distance during key moments by 65 %, the time to complete selected operations by 40 % and manpower necessity by 50 % in 75 % of analyzed work operations.