EFFEKTER AV FYSISK TRÄNING HOS PERSONER MED DUCHENNES-,  BECKERS OCH LIMB-GIRDLE MUSKELDYSTROFI : En systematisk litteraturstudie

Sammanfattning: Background: There is currently no curative treatment method for muscular dystrophy. Physical therapy is extremely important for maintaining the physical functions and delaying the breakdown of muscles that occurs in the affected. Theories say low-intensity training produces positive effects, while high-intensity training speeds up muscle breakdown. However, the evidence and the knowledge of how an optimal training program should be performed for these patient groups is limited.   Objective: To map and compile the effects of physical training in persons with Duchennes, Beckers and Limb-girdle muscular dystrophy, and to evaluate the quality of the studies. Method: A systematic review was performed in two databases; PubMed and PEDro. Six studies, three RCT studies and three experimental studies, were found. The studies quality was assessed by using quality templates from SBU. From these studies, relevant data were then extracted to answer the questions of this study.  Results: Four studies provided low-intensity physical training, two moderate-intensity, and one study also included high-intensity training, as interventions. The interventions lasted for 8–24 weeks and focused mainly on aerobic capacity, muscle strength and mobility. All studies showed some type of significantly positive effects through its intervention. The studies were judged to have limited quality and evidence strength. Conclusions: Low-intensity training showed significant improvements in muscle strength, endurance, mobility, and functional movements. The improvements varied depending on the study's intervention design. High-intensity training seems to be harmful to these patient groups. More research, especially more randomized controlled studies, is needed in this field.