Simulate Bacterial Movement through Chemotaxis

Detta är en Kandidat-uppsats från Göteborgs universitet/Institutionen för data- och informationsteknik

Sammanfattning: This thesis describes the development of an agent-based simulation of E. coli chemotaxis in C# and the Unity game engine. The agents use a mathematical modelof the chemical pathway underlying chemotaxis to produce either forward-motion(running) or rotation (tumbling), in response to the concentration of ligand in theirimmediate environment. This model consists of a system of ODEs from Edgingtonand Tindall [1] and elements of survival analysis. A tool for analysing data fromthese simulations was also developed, and used to make quantitative comparisonsbetween simulations. This is used to compare our model to a simplified modelof chemotaxis, designed to always display chemotactic behaviour. It is concludedthat both models display chemotactic movement, with the simplified model beingmore effective at finding the ligand source, but the ODE-based model being moreadaptive.

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