Prototype algorithm development for innovative sensor technology

Sammanfattning: Preterm infants are sensitive to incorrect levels of oxygen in the blood. Thus, the oxygen levels need to be monitored continuously. The most commonly used method today has several limitations and therefore constant blood tests has to be taken. Neosense Technologies AB has developed an electrochemical sensor that measures blood oxygen tension continuously and in real time. This thesis aims to develop a prototype algorithm to derive cardiac output based on dynamic changes in inhaled fraction of oxygen and the corresponding change in arterial oxygen tension using the electrochemical sensor. Two measurements were done using the sensor to measure the step response of partial pressure of oxygen to obtain data to develop the algorithm. Using the obtained data, two algorithms were developed and from the validation analysis one of the algorithms were chosen due to significant better results.