Evaluation of 3D MRI Image Registration Methods

Sammanfattning: Image registration is the process of geometrically deforming a template image into a reference image. This technique is important and widely used within thefield of medical IT. The purpose could be to detect image variations, pathologicaldevelopment or in the company AMRA’s case, to quantify fat tissue in variousparts of the human body.From an MRI (Magnetic Resonance Imaging) scan, a water and fat tissue image isobtained. Currently, AMRA is using the Morphon algorithm to register and segment the water image in order to quantify fat and muscle tissue. During the firstpart of this master thesis, two alternative registration methods were evaluated.The first algorithm was Free Form Deformation which is a non-linear parametricbased method. The second algorithm was a non-parametric optical flow basedmethod known as the Demon algorithm. During the second part of the thesis,the Demon algorithm was used to evaluate the effect of using the fat images forregistrations.