Ett nytt semantiskt intraoperativt test på svenska : Baserat på DuLIP:s semantic odd word out

Sammanfattning: Low-grade gliomas (LGGs) constitute a major challenge for health care because of their location and nature. LGGs are often found in eloquent areas, and their infiltrative growth cause neurological reorganization, which complicates the mapping of important functions. Awake surgery in combination with direct electrical stimulation (DES) and intraoperative tests is a relatively new method for mapping the brain's functional limits, thus eliminating as much of the tumor as possible while maintaining important functions. At present there is no available intraoperative test for semantic processing in Swedish. Tests of specific linguistic abilities improves the specificity of mapping which reduces post-operative linguistic impairments. Intraoperative tests can thus contribute to increased quality of life in the patient group. This study was based on the Dutch Lingusistic Intraoperative Protocol (DuLIP) test battery to create a Swedish version of the subtest semantic odd word out (SOWO). SOWO tests semantic processing via lexical reading. The adjusted and extended version of SOWO was tested during a pilot trial on 26 standard-language people. The study has resulted in a new semantic intraoperative test in Swedish that will be clinically examined at University Hospital in Uppsala. Hopefully, the new test contributes to better treatment options for patients with LGG.