Sökning: "CSF biomarkers"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden CSF biomarkers.

  1. 1. Development of Sandwich Assays for Potential Protein Biomarkers in Neurodegenerative Diseases

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Jamil Yousef; [2020]
    Nyckelord :Biomarkers; cerebrospinal fluid; neurodegenerative diseases; neuroproteomics; sandwich assay; suspension bead array.; Biomarkörer; ryggmärgsvätska; neurodegenerativa sjukdomar; neuroproteomik; sandwich assay; suspension bead array.;

    Sammanfattning : As the aging population is increasing worldwide, so is the prevalence of neurodegenerativediseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia(FTD) and amyotrophic lateral sclerosis (ALS). Reliable biomarkers able to aid the diagnosis anddifferentiation of these diseases are needed in order to start the right treatment as early as possible. LÄS MER

  3. 2. An Alzheimer-type cerebrospinal fluid profile in early Parkinson's disease

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för psykologi

    Författare :Mario-Christofer Chamoun; [2019]
    Nyckelord :Parkinson s disease; Parkinson sjukdom;

    Sammanfattning : In recent years, several studies have discovered traces of Alzheimer's (AD) biomarkers in a large portion of patients with Parkinson's disease (PD), which have been associated with subsequent dementia (PDD). However, the manifestation of AD biomarkers in PD is not fully understood. LÄS MER

  4. 3. Tau phosphorylation on threonine 217 as a potential biomarker for neurodegenerative diseases

    M1-uppsats, Högskolan i Borås/Akademin för textil, teknik och ekonomi

    Författare :Sukri Omar Jama; [2019]
    Nyckelord :P217; hyperphosphorylation; Taupathies; CSF; plasma; serum; Simoa; antibodies; assay; Progressive supranuclear palsy; Alzheimer’s disease and Global glial Taupathies; P217; hyperfosforyrlering; Taupathies; CSF; plasma; serum; Simoa; antikroppar; analys; Progressiv supranukleär pares; Corticobasal degeneration och Globular glialtauopati;

    Sammanfattning : Hyperfosforylering av biomarkörproteinet Tau förekommer i flera neurodegenerativa sjukdomar som kallas Taupathies. Proteinets huvudfunktion i människokroppen är att modulera flexibilitet och stabilitet för axonal-mikrotubulin. I Taupathies utlöser hyperfosforyleringen av Tau instabilitet och neurodegenerationen. LÄS MER

  5. 4. CSF biomarkers related to sleep, cognition and neuroinflammation in patients with Kleine Levin Syndrome

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Nora Euler; [2018]
    Nyckelord :;

    Sammanfattning : Kleine Levin Syndrome (KLS) is a hypersomniac disease of episodic nature that affects only 1-5 per million individuals globally. In addition to extensive periods of sleep (> 20 hours) patients experience a wide range of symptoms during an episode, which occur approximately 1-12 times a year with a median of 10 days. LÄS MER

  7. 5. Resting state fMRI as a marker for progression from mild cognitive impairment to Alzheimer’s disease

    Master-uppsats, Lunds universitet/Sjukhusfysikerutbildningen

    Författare :Tor Olof Strandberg; [2014]
    Nyckelord :Medicine and Health Sciences;

    Sammanfattning : The arc of progression in the most common neurological aiction known as Alzheimer's Disease (AD), is characterized by a prodromal stage of Mild Cognitive Impairment (MCI). MCI subjects have traditionally been diagnosed with a battery of cognitive tests, but in recent times two good biomarker predictors of incipient AD have been identied. LÄS MER