Sökning: "pro-inflammatory cytokines"
Visar resultat 1 - 5 av 26 uppsatser innehållade orden pro-inflammatory cytokines.
1. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model
Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)Sammanfattning : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. LÄS MER
2. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. LÄS MER
3. GSK-3 post-transcriptionally regulates TNF-α biosynthesis in THP-1 macrophages
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Few things are more fascinating than finding new interactions between previously unrelated pathways. Glycogen synthase kinase-3 (GSK-3), a ubiquitous kinase initially known for its role in regulating glycogen metabolism, has recently been found to be an indispensable regulator of the TLR4-mediated inflammatory response. LÄS MER
4. Factors and mechanisms associating the mobilisation of Ca2+ with the activation of the NLRP3 inflammasome : A systematic review
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammasomes are multiprotein complexes that play a critical role in the regulation of inflammation and the inflammatory responses against pathogens. NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3) is among the molecules involved in the homonymous and well-studied NLRP3 inflammasome that accounts for the release of the pro-inflammatory cytokines interleukin (IL) 1-β and 18. LÄS MER
5. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. LÄS MER
