Sökning: "Lipid nanoparticle"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden Lipid nanoparticle.

  1. 1. Exploring alternative surfactants to replace PEG within lipid nanoparticles

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

    Författare :Elina Edidovica; [2024]
    Nyckelord :Lipid nanoparticle; polyethelyne glycol PEG ; alpha-tomatine; N-hexadecyl beta d-maltoside HDM ; DOPC; DPPC; cholesterol; film hydration; stability study; DLS; Cryo-TEM; SAXS; pharmaceutical formulation; Chemistry;

    Sammanfattning : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. LÄS MER

  3. 2. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Tasnim Yasin Idris; [2022]
    Nyckelord :affibody; phage display; in vitro selection; CD5; CD8; CD19; CAR T-cell therapy.;

    Sammanfattning : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. LÄS MER

  4. 3. Nanoparticle-supported lipid bilayers : A novel approach to introduce curvature in model membranes

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för integrativ medicinsk biologi (IMB)

    Författare :Wourood Hussein; [2021]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Exosomes and lipid nanoparticles - the future of targeted drug delivery

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Sara Lundberg; Emelia Karlsson; Hugo Dahlberg; Mathilda Glansk; Sara Larsson; Sofia Larsson; Karl Carlsson; [2020]
    Nyckelord :Exosomes; lipid nanoparticles; drug delivery;

    Sammanfattning : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. LÄS MER

  7. 5. Prominent variable detection in lipid nanoparticle experiments : A simulation study on non-parametric change point analysis

    Master-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Hongru Zhai; [2020]
    Nyckelord :;

    Sammanfattning : Images as important sources of information, powered by the newest robotic microscopy technologies, make the volume of data available larger than ever before. From the images, hundreds of variables can be calculated. LÄS MER