Sökning: "Macromolecular crowding"

Hittade 1 uppsats innehållade orden Macromolecular crowding.

  1. 1. Macromolecular Crowding as a Determinant of Protein Viability -- a Lattice Model Study

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Daniel Nilsson; [2017]
    Nyckelord :Protein folding; Macromolecular crowding; HP model; Physics and Astronomy;

    Sammanfattning : We study the effects of macromolecular crowding with interacting crowders in the simple HP-model of protein folding, by performing Monte Carlo simulations of a single flexible HP protein in the presence of folded rigid crowders. In contrast to the well-known stabilization of steric crowders, we find that interacting crowders usually destabilize the test protein, often significantly so. LÄS MER