Sökning: "clinical pathways"

Visar resultat 1 - 5 av 33 uppsatser innehållade orden clinical pathways.

  1. 1. Examination of pathway crosstalk and functional modules in papillary thyroid cancer dedifferentiation to anaplastic thyroid cancer

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Maria Panagiota Theodorou; [2023]
    Nyckelord :;

    Sammanfattning : Thyroid cancer, comprising well-differentiated follicular and papillary types, alongside less common medullary and anaplastic subtypes with poor prognoses, exhibits specific anaplastic cases resulting from papillary dedifferentiation, lacking precise molecular evidence. Utilizing Metascape, CTpathway and PathwAX II, the study integrates functional modules and pathway crosstalk for dedifferentiation analysis, conducting a comprehensive two-dimensional assessment of toolset’s functionality, compatibility, and interoperability. LÄS MER

  3. 2. Constructing and analyzing a gene-gene interaction network to identify driver modules in lung cancer using a clustering method

    Magister-uppsats, Stockholms universitet/Institutionen för data- och systemvetenskap

    Författare :Marcell Szalai; [2023]
    Nyckelord :Lung Cancer; Driver Modules; Artificial Intelligence; Clustering; Gene-Gene Interaction Network; Signaling Pathways;

    Sammanfattning : Cancer is a complex disease with diverse genetic changes that pose significant treatment challenges due to its heterogeneity. Identifying driver modules, which are crucial for cancer progression, has been aided by artificial intelligence (AI) techniques. However, existing approaches lack specificity, particularly for cancer types like lung cancer. LÄS MER

  4. 3. Nursing interventions for patients with stroke : A descriptive review

    Kandidat-uppsats, Högskolan i Gävle/Avdelningen för vårdvetenskap

    Författare :Jing Chen; Peiwen Qiu; [2023]
    Nyckelord :;

    Sammanfattning : Background: Stroke is a global health problem, which affects more than 15 millionpeople each year worldwide and leads to high mortality and disability rates. Theprevalence and incidence of stroke in an aging population continued to rise, and somescholars estimated that by 2030, the incidence of stroke was expected to increase toabout three times the current incidence. LÄS MER

  5. 4. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Leo Svahn; [2023]
    Nyckelord :NRF2; KEAP1; THP-1; M1; M2; SLE;

    Sammanfattning : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. LÄS MER

  7. 5. Är AMX0035 nästa vapen i kampen mot amyotrofisk lateralskleros?

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Amelia Sundström; [2022]
    Nyckelord :Amyotrofisk lateralskleros; riluzol; AMX0035; natrium 4-fenylbutyrat; taurursodiol;

    Sammanfattning : Introduktion: Förekomsten av neurodegenerativa sjukdomar ökar, där ibland amyotrofisk lateralskleros (ALS) vilket gör att behovet efter nya effektiva terapier växer. ALS är en progressiv sjukdom som kännetecknas utav en degeneration av de övre motorneuronen i motoriskt cortex och de nedre motorneuronen i hjärnstam och ryggmärg. LÄS MER