Sökning: "coagulation assay"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden coagulation assay.

1. 1. Characterization of a novel EPHB2 R155C mutant with respect to its proteolytic cleavage by TF/FVIIa

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Ece Akcan; [2021]
   Nyckelord :cancer; colorectal cancer; CRC; ephrin receptor; EPHB2; tissue factor; TF; TF FVIIa; cleavage; cell repulsion;

   Sammanfattning : EPHB2, an ephrin receptor (EPH) from receptor tyrosine kinase (RTK) family, is one of the substrates for tissue factor (TF) - coagulation factor VIIa (FVIIa) complex and it is cleaved in its ectodomain. EPHB2 cleavage is important for ephrin receptor (EPH) - ephrin ligand (EFN) signaling and cell repulsion. LÄS MER

3. 2. Utvärdering av analysmetod för bestämning av anti-FXa aktivitet i plasma hos patienter behandlade med apixaban eller LMH

   Kandidat-uppsats, Högskolan i Jönköping/HHJ, Avd. för naturvetenskap och biomedicin

   Författare :Areej Abuaita; Asmaa El Saleh; [2019]
   Nyckelord :NOAC. Chromogenic substrate assay. Eliquis. Fragmin. blood coagulation.; NOAK. Kromogen substratmetod. Eliquis. Fragmin. blodkoagulation.;

   Sammanfattning : Apixaban och lågmolekylärt heparin (LMH) är antikoagulantia som förhindrar blodproppsbildning genom att hämma faktor Xa. Allt mer patienter använder apixaban och LMH, vilket gör att laboratoriemedicin på länssjukhuset Ryhov är i behov av att utvärdera analysmetoder för apixaban och LMH för att kunna implementera analyserna i klinisk rutin. LÄS MER

4. 3. Nanoparticle size-dependent activation of the hemostasis and the innate immune system.

   Kandidat-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi

   Författare :Johanna Sundström; [2016]
   Nyckelord :;

   Sammanfattning : Nanoparticles are small particles with a size range of 10-1000 nm. They exist all around us, in make-up, dust and even food. They can enter our bloodstream through different pathways such as inhalation and cause thrombosis and multiple organ failure. LÄS MER

5. 4. Evaluation of a Viscosity/Elasticity Assay (ReoRox®) for Assessment of Platelet Storage Lesion and Fibrinogen Dependent Coagulation

   Kandidat-uppsats, Uppsala universitet/Institutionen för kvinnors och barns hälsa

   Författare :Erla Guðjónsdóttir; [2016]
   Nyckelord :Thrombine receptor activator peptide TRAP ; aggregability; free oscillation rheometry FOR ; fibrinolysis; blood clot.;

   Sammanfattning : The impact storage has on function of platelet concentrates is not completely known, although some factors have been discovered and measures have been taken to counteract them, such as adding platelet additive solution. There are several methods for analysing platelet function. LÄS MER

7. 5. The effect of prophylactic platelet transfusions on point-of-care coagulation parameters in conjunction to central venous catheter insertion—what effect do transfusions have and are they necessary?

   Master-uppsats, Lunds universitet/Läkarutbildningen

   Författare :Johan Hahr Schoug; [2012]
   Nyckelord :Platelet; Platelet transfusion; Thromboelastography; Thromboelastometry; Platelet aggregometry; ROTEM; Multiplate; Central venous catheter; CVC; Thrombocytopenia; Coagulation; Thrombocyte; Platelet function; Cancer; Hematological malignancy; Leukemia; Medicine and Health Sciences;

   Sammanfattning : Introduction: Platelet transfusions are often used when thrombocytopenic patients are facing a central venous catheter (CVC) insertion, but their use has been up to debate. Point-of-care devices such as thromboelastometry (ROTEM) and platelet aggregometry (Multiplate) better reflect in vivo haemostasis than routine coagulation tests. LÄS MER