Sökning: "type I interferons"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden type I interferons.

  1. 1. Role of androgen receptor signaling in the activation and differentiation of plasmacytoid dendritic cells

    Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

    Författare :Faiza Tahsin Rashid; [2023-06-27]
    Nyckelord :;

    Sammanfattning : Androgens are steroid hormones essential for the development and maintenance of male reproductive organs and secondary sexual characteristics. Plasmacytoid dendritic cells (pDCs) are immune cells that act as the first line of defense against viral infections. LÄS MER

  3. 2. Investigating the autoimmunity profiles of Covid-19 patients

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alfred Kedhammar; [2021]
    Nyckelord :Covid-19; SARS-CoV-2; Autoimmunity; Autoantibodies; Cytokines; Covid-19; SARS-CoV-2; Autoimmunitet; Autoantikroppar; Cytokiner;

    Sammanfattning : The clinical severity of Covid-19 varies greatly between individuals, and all underlying risk factors are not yet well understood. Previous studies have shown Covid patients to be enriched with autoantibodies against type I interferons, suggesting autoimmunity may be an underlying factor of susceptibility to severe disease. LÄS MER

  4. 3. Behandling av kronisk myeloisk leukemi med tyrosinkinasinhibitorer i samband med graviditet

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Fatima Muhson; [2019]
    Nyckelord :TKI; tyrosinkinashämmare; KML; imatinib; nilotinib; dasatanib; bosutinib; ponatinib;

    Sammanfattning : Bakgrund: Vid kronisk myeolid leukemi (KML) överproducerar blodstamceller omogna granulocyter som kan öka risken för infektioner, anemi och lätta blödningar. Ifall sjukdomen inte åtgärdas i tidigt skede så kan cancercellerna konkrurera ut friska blodceller vilket kan leda till ett livshotande tillstånd. LÄS MER

  5. 4. Comparison of the immunomodulatory capabilities of the V and C proteins of different morbilliviruses

    Master-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Nelman Pushpa D Ranasinghe Atapattu Mudiyanselage; [2018]
    Nyckelord :Feline morbillivirus; Canine distemper morbillivirus; Measles morbillivirus; Type I interferon; C protein; V protein;

    Sammanfattning : During a viral infection, when the virus enters into the cytoplasm, different cell types are able to produce interferons (IFN) as a result of interaction between intracellular pattern recognition receptors (PRR) and RNA helicases. This interferon activates and establishes an antiviral state which limits further spread of the virus. LÄS MER

  7. 5. Evaluation of the gene expression of STING, IFN‐β and osteopontin in tissue obtained from pigs treated with Matrix‐M

    Master-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Navisraj Balagunaseelan; [2014]
    Nyckelord :STING ; OPN; MATRIX‐M; type I interferons;

    Sammanfattning : Matrix‐M is the adjuvant component in traditional ISCOM vaccines. The adjuvant when used along with antigen increases the efficiency of the vaccines by inducing a balanced Th1/Th2 response and a long‐lasting antibody response. LÄS MER