Sökning: "dna transcription"

Visar resultat 1 - 5 av 44 uppsatser innehållade orden dna transcription.

  1. 1. Towards time-resolved cryo-EM of SARS-CoV-2 replication-transcription complex and Staphylococcus aureus DNA gyrase

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Anna Králová; [2023]
    Nyckelord :time-resolved cryo-EM; DNA gyrase; SARS-CoV-2; replication-transcription complex; protein purification;

    Sammanfattning : Time-resolved cryo-EM has already provided ground-breaking discoveries in various fields, including structural biology, biochemistry, and drug development. Compared to traditional structural biology methods where mostly stabilized conformations are reconstructed, the main advantage of time-resolved cryo-EM is its ability to capture dynamic processes in biological samples at near-atomic resolution, which allows for studying biological structures as they change and interact in real-time. LÄS MER

  3. 2. Knockout of transcription factor MYB28 by CRISPR/Cas9 for reducing glucosinolate content in rapeseed (Brassica napus L.)

    Master-uppsats, SLU/Dept. of Plant Breeding (from 130101)

    Författare :Anusha Harshani Bogahawatta; [2023]
    Nyckelord :CRISPR Cas9; Glucosinolates; ; MYB28; protoplast; ; rapeseed; ; ribonucleoprotein; ; transcription factor;

    Sammanfattning : Rapeseed cake is a protein-rich by-product from the rapeseed oil extraction process. It contains high levels of glucosinolates (GSLs), which possess anti-nutritional functions after being hydrolyzed. Moreover, the hydrolyzed products of GSLs produce an extremely bitter taste. LÄS MER

  4. 3. Investigation of the interaction of A-MYB and TCFL5 on pachytene PIWI-interacting RNA genes in two sub-species of mice, mus musculus musculus and mus musculus castaneus

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Most Shova Banu; [2023]
    Nyckelord :;

    Sammanfattning : Spermatogenesis is a complex process that involves the production of sperm cells from germ cells in order to transmit genetic information to progeny. The PIWI-interacting RNA (piRNA) is a non-coding small silencing RNA that guides the PIWI protein to silence target transposon transcripts to regulate the production of germ cells. LÄS MER

  5. 4. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Leo Svahn; [2023]
    Nyckelord :NRF2; KEAP1; THP-1; M1; M2; SLE;

    Sammanfattning : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. LÄS MER

  7. 5. Understanding the pathophysiology ofrecurrent UBTF mutations associated withpediatric AML

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Annie Paulsson; [2022]
    Nyckelord :Hematologi; Cancer; AML; UBTF; leukemi;

    Sammanfattning : Acute myeloid leukaemia (AML) is highly heterogeneous haematological malignancy, which represents a challenge in the understanding of the disease. Relapse in AML is common, andmany relapsed patients respond poorly to conventional treatment, leading to a low survivalrate. LÄS MER