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Visar resultat 1 - 5 av 7 uppsatser som matchar ovanstående sökkriterier.

  1. 1. Development of a novel method for studying permeability of PEG-ylated liposomes

    Master-uppsats, Uppsala universitet/Institutionen för kemi - Ångström

    Författare :Jicheng Li; [2021]
    Nyckelord :;

    Sammanfattning : PEG-ylated liposomes are attractive in terms of utilizing them as long-circulating drug carriers. With the incorporation of PEG-components in the liposomal membranes, their permeability towards small-molecule solutes may be affected for various reasons. LÄS MER

  3. 2. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Venus Zafranian; [2021]
    Nyckelord :Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

    Sammanfattning : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. LÄS MER

  4. 3. Convolutional neural networksfor classification of transmissionelectron microscopy imagery

    Master-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Sergii Gryshkevych; [2017]
    Nyckelord :;

    Sammanfattning : One of Vironova's electron microscopy services is to classify liposomes. This includes determining the structure of a liposome and presence of a liposomal encapsulation. A typical service analysis contains a lot of electron microscopy images, so automatic classification is of great interest. LÄS MER

  5. 4. Circumventing Gemcitabine resistance in pancreatic cancer using drug delivery systems

    Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Gabriella Willman; [2017]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Gemcitabine is the first line treatment of pancreatic cancer, a treatment that is relying on the expression of human Equilibrative Nucleoside Transporter 1 for cellular uptake. Combined with its short blood half-life and intracellular activation steps, Gemcitabine treatment has many limitations. LÄS MER

  7. 5. Formulation and characterization of liposomal spray dried powders intended for inhalation

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Fredrik Kullenberg; [2016]
    Nyckelord :Impactor; Phospholipid; Liposome; Spray Drying; Inhalation; Fine Particle Fraction; Pharmaceutical Technology; läkemedelsteknologi; Medicine and Health Sciences; Technology and Engineering;

    Sammanfattning : This master thesis has evaluated the possible use of a spray dryer to produce powders suitable for use as inhalants and whether the addition of liposomes to the solution to be spray dried would improve the properties of the powder. The powders created consisted of Lysozyme as model drug, Lactose as filler and stabilizer, and different types of phospholipids to create liposomes using an ethanol injection method. LÄS MER