Sökning: "dissolution profiles"

Hittade 5 uppsatser innehållade orden dissolution profiles.

  1. 1. Impact on dissolution rate of oral solid dosage forms by increasing the temperature and paddle speed with fully automated dissolution robot SingBATH

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Hamad Hamid; [2022]
    Nyckelord :SingBATH; Fully automated dissolution robot; dissolution rate; temperature; RPM of paddle;

    Sammanfattning : The pharmaceutical dosage forms usually undergo a test which is intended for assessing in-vitro performance called the dissolution test. Apart from the drug formulation, factors which can affect dissolution rate include revolutions per minute (RPM) of paddle, temperature of the system and cloud point of the excipients. LÄS MER

  3. 2. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Venus Zafranian; [2021]
    Nyckelord :Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

    Sammanfattning : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. LÄS MER

  4. 3. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Maral Simonides; [2021]
    Nyckelord :Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

    Sammanfattning : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. LÄS MER

  5. 4. Mapping of contaminant dispersion from a polluted mining area by geochemical and geophysical methods, Rävlidmyran,northern Sweden : Use of geochemical and geophysical studies to investigate contaminants

    Uppsats för yrkesexamina på avancerad nivå, Luleå tekniska universitet/Institutionen för samhällsbyggnad och naturresurser

    Författare :Astrid Theander; [2019]
    Nyckelord :;

    Sammanfattning : After open pit mining, the pit can either be backfilled or be filled with groundwater andbecome a pit lake. These lakes tend to be acidic and contains high concentrations ofmetals, which increases the environmental risks in the area. One of these pit lakes isRävlidmyran in the Skellefte ore district. LÄS MER

  7. 5. Mineralogical speciation of sulfur in acid sulfate soils from Luleå, Sweden

    Uppsats för yrkesexamina på avancerad nivå, Luleå tekniska universitet/Geovetenskap och miljöteknik

    Författare :Niklas Gunnarsson; [2018]
    Nyckelord :acid sulfate soil; metal leakage; low pH; SEM; elemental sulfur; framboidal pyrite;

    Sammanfattning : Marine sulfide – bearing sediments that oxidize when in contact with oxygen and leach outelements in high concentrations to small watercourses have been a problem for many years allover the world especially around the Bothnian Bay. The purpose of this study was to furtherinvestigate the sulfur mineralogy present in acid sulfate soils in the area of Luleå, Sweden. LÄS MER