Sökning: "Dynamic Contrast-Enhanced MRI"

Hittade 4 uppsatser innehållade orden Dynamic Contrast-Enhanced MRI.

1. 1. Validation and Robustness Analysis of Dynamic Contrast Enhanced MRI

   Master-uppsats, Umeå universitet/Institutionen för fysik

   Författare :Samuel Fransson; [2015]
   Nyckelord :MRI; DCE-MRI; Dynamic Contrast Enhanced MRI; Validation; Simulation;

   Sammanfattning : In Dynamic Contrast Enhanced MRI there are several steps from the initial signal to obtaining the pharmacokinetic parameters for tumor characterization. The aim of this work was to validate the steps in the flow of data focusing on T1-mapping, Contrast Agent (CA)-quantification and the pharmacokinetical (PK) model, using a digital phantom of a head. LÄS MER

3. 2. Improving the Modeling Framework for DCE-MRI Data in Hepatic Function Evaluation

   Master-uppsats, Institutionen för medicin och hälsa; Hälsouniversitetet

   Författare :Anneli Mossberg; [2013]
   Nyckelord :DCE-MRI; modeling; irregular sampling; spatio-temporal standard deviation estimation; sampling time optimization; regional optimization; liver function evaluation; systems biology;

   Sammanfattning : Background Mathematical modeling combined with prior knowledge of the pharmacokinetics of the liver specific contrast agent Gd-EOB-DTPA has the potential to extract more information from Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) data than previously possible. The ultimate goal of that work is to create a liver model that can describe DCE-MRI data well enough to be used as a diagnostic tool in liver function evaluation. LÄS MER

4. 3. Human Whole Body Pharmacokinetic Minimal Model for the Liver Specific Contrast Agent Gd-EOB-DTPA

   Magister-uppsats, Medicinsk radiofysik; Hälsouniversitetet

   Författare :Mikael Fredrik Forsgren; [2011]
   Nyckelord :Gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid; Dynamic Contrast-Enhanced MRI; Pharmacokinetics; Liver; Ordinary Differential Equation; Mathematical Modeling; Systems Biology;

   Sammanfattning : Magnetic resonance imaging (MRI) of the liver is an important non-invasive tool for diagnosing liver disease. A key application is dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). With the use of the hepatocyte specific contrast agent (CA) Gd-EOB-DTPA it is now possible to evaluate the liver function. LÄS MER

5. 4. Feasibility Study of Phase Measurements of the Arterial Input Function in Dynamic Contrast Enhanced MRI

   Master-uppsats, Radiofysik

   Författare :Sandra Marklund; [2009]
   Nyckelord :AIF; Arterial Input Function; DCE-MRI; Dynamic Contrast Enhanced MRI; MRI; Gd; Gadolinium; Phase measurement; Phase;

   Sammanfattning :   Acquired data from dynamic contrast enhanced MRI measurements can be used to non-invasively assess tumour vascular characteristics through pharmacokinetic modelling. The modelling requires an arterial input function which is the concentration of contrast agent in the blood reaching the volume of interest as a function of time. LÄS MER