Sökning: "Olga Golovko"

Hittade 1 uppsats innehållade orden Olga Golovko.

  1. 1. The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.

    Kandidat-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Olga Golovko; [2011]
    Nyckelord :Anticancer drug development; proteasome inhibition; chemotherapy; image-based screening assay; FMCA.;

    Sammanfattning : The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation. LÄS MER