Sökning: "cdk4 6 inhibitors"

Hittade 2 uppsatser innehållade orden cdk4 6 inhibitors.

1. 1. Role of CDK4/CDK6 inhibitors: Ribociclib, Palbocilcib and Abemacilcib in treatment of metastatic breast cancer

   Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

   Författare :Nazanin Ghobadpour; [2021]
   Nyckelord :Breast cancer; cdk4 6 inhibitors; Bröstcancer; cdk4 6 hämmare;

   Sammanfattning : Breast cancer is the most common cancer among women in Sweden and globally. Socio-demographic, genetic and productive factors together with some endogenous and exogenous hormones and lifestyle are some of the risk factors that can cause this type of cancer. LÄS MER

3. 2. Risk of neutropenia and healthcare resource utilization in patients with metastatic breast cancer treated with CDK4/6 inhibitors in real-world setting

   Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

   Författare :Anna Bergkvist; [2021]
   Nyckelord :;

   Sammanfattning : Introduction: In patients with metastatic estrogen-receptor (ER) positive breast cancer, the current standard of care as first or second line treatment is a combination of endocrine therapy with a CDK 4/6-inhibitor. Neutropenia is a dose-limiting toxicity of CDK 4/6 inhibitors leading to dose adjustment and treatment discontinuation in a considerable number of patients. LÄS MER