Sökning: "gene therapy"

Visar resultat 1 - 5 av 59 uppsatser innehållade orden gene therapy.

  1. 1. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    Master-uppsats, Lunds universitet/Institutionen för immunteknologi

    Författare :Johan Thorsson; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. LÄS MER

  3. 2. Novel Therapy against Malaria Resistance using Meta-analysis

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Adesola Oguntuyi; [2022]
    Nyckelord :Malaria; Novel Drug; Resistance; ACT;

    Sammanfattning : Malaria causes severe illness and death in some cases if not treated on time. The most vulnerable people are children and pregnant women in areas where it is rampant. The causative agent of the most severe malaria is Plasmodium falciparum this parasite is transmitted by the female anopheles mosquito when infected with Plasmodium parasites. LÄS MER

  4. 3. Non-coding RNAs as therapeutic agents : The future of therapy

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
    Nyckelord :Non-coding RNA; Oligonucleotide therapeutics;

    Sammanfattning : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. LÄS MER

  5. 4. Novel mRNA therapeutics for cardiomyogenesis and vasculogenesis

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Xiaoting Huang; [2022]
    Nyckelord :Heart; Placental growth factor PLGF ; Cardiomyogenesis; Vasculognesis; Regeneration; hjärta; PLGF; kardiomyogenes; vaskulogenes; regenerering;

    Sammanfattning : Kardiovaskulära sjukdomar är fortfarande en av de främsta dödsorsakerna i dag. Den främsta orsaken till sjukdomen är skador på hjärtcellerna, som kanske inte kan repareras av sig själva, så att utveckla en ny terapi för att regenerera eller reparera hjärtcellerna är ett viktigt mål inom forskningen om hjärtsjukdomar. LÄS MER

  7. 5. Quantification of the expression of hsa-mir-34c-5p in neuroblastoma cells

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Lorena Trissl; [2022]
    Nyckelord :;

    Sammanfattning : Neuroblastomas are the most common extra-cranial abnormal growths in immature nerve tissue within the sympathetic nervous system, in children ages 0-5. It is a heterogeneous malignancy, often emerging in and around adrenal glands, caused by rapid growth and division of nerve cells. LÄS MER