Sökning: "Plasmids"

Visar resultat 1 - 5 av 55 uppsatser innehållade ordet Plasmids.

  1. 1. Gene expression editing in myeloma cell lines using CRISPR/Cas9 technique

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Wilma Wadman; [2023]
    Nyckelord :BMPR1A; BMPR2; bone morphogenetic protein; gene knockout; multiple myeloma;

    Sammanfattning : Multiple myeloma, or myeloma, is a bone marrow cancer which characterizes by uncontrolled proliferation of mutant plasma cells. It is a disease that claims many lives every year, mostly due to the absence of curative treatment. Finding a suitable treatment is therefor of great importance. LÄS MER

  3. 2. Insulated Metabolic Exchange for Sustainable Agriculture and Biotechnology

    Master-uppsats, KTH/Industriell bioteknologi

    Författare :Ellen Engquist; [2023]
    Nyckelord :Biofertilisers; nitrogen; cyanobacteria; E. coli; allantoin; Biogödsel; kväve; cyanobakteria; E. coli; allantoin;

    Sammanfattning : Mellan 1960 och idag har världspopulationen dubblerats medan matproduktionen tredubblats. Det har möjliggjorts av kemiskt framställda gödsel som introducerades på mitten av 1900-talet. Sedan 1965 har användandet av kvävegödsel ökat sexdubblet. LÄS MER

  4. 3. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Jonathan Efverström; [2023]
    Nyckelord :Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

    Sammanfattning : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. LÄS MER

  5. 4. The effect of TRAP150 on HPV16 E1 gene regulation

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Emma Svanberg Frisinger; [2023]
    Nyckelord :;

    Sammanfattning : Human papilloma virus (HPV) is a small DNA virus that is known as the causative agent in cervical cancer. The virus is found worldwide and causes more than 300 000 deaths yearly. Although there are many types of HPV, HPV16 is found in 99 % of cervical cancer cases. LÄS MER

  7. 5. The battle against sepsis : exploring the genotypic diversity of pseudomonas and proteus clinical isolates

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Suud Ahmed; [2023]
    Nyckelord :;

    Sammanfattning : Sepsis is a dangerous and potentially fatal condition that has a mysterious origin, underscoring the significance of prompt and accurate diagnosis and treatment. Bacterial whole-genome sequencing, which is widely used in clinical microbiology, stands at the forefront of sequencing technologies, particularly to combat sepsis. LÄS MER