Sökning: "Deep brain stimulation"

Visar resultat 1 - 5 av 27 uppsatser innehållade orden Deep brain stimulation.

  1. 1. Integration of Deep Brain Stimulation Modeling Tools

    Master-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Lina Wilhelmina Sundqvist; [2023]
    Nyckelord :;

    Sammanfattning : Deep brain stimulation is a treatment in which neural targets are stimulated by electrical pulses delivered through implanted leads to alleviate symptoms in certain neurological- and psychiatric disorders. To achieve a beneficial clinical outcome, adjusting the stimulation parameters is a crucial step, which, at present, is a tedious and difficult trial-and-error procedure. LÄS MER

  2. 2. EVOKED PHASE COHERENCE AS A BIOMARKER FOR ADAPTIVE NEUROMODULATION IN RAT MODEL OF PARKINSON'S DISEASE

    Master-uppsats, Umeå universitet/Institutionen för psykologi

    Författare :Love Zackrisson; [2023]
    Nyckelord :Adaptive; Closed Loop; Neuromodulation; Parkinson’s Disease; Rat model; 6-OHDA; ITC; Phase Coherence; Bayesian Model; Classifier; Spinal Cord Stimulation; Deep Brain Stimulation.; Adaptiv; Closed Loop; Neuromodulation; Parkinson’s Sjukdom; Råttmodell; 6-OHDA; ITC; Faskoherens; Bayesiansk Modell; Klassificerare; Ryggradsstimulering; Djup Hjärnstimulering.;

    Sammanfattning : Neuromodulation, such as spinal cord stimulation (SCS) and deep brain stimulation (DBS), has been shown to modulate pathophysiological brain activity and provide symptomatic therapy for several neurological disorders, including Parkinson’s Disease. The effectiveness of this therapy could likely be further improved by neuromodulation that is adaptive, delivering stimulation more selectively, by monitoring a biomarker in recorded brain signals, which indicates the presence of a pathological state. LÄS MER

  3. 3. Kan djup hjärnstimulering utgöra en effektiv behandling hos behandlingsresistenta personer med tvångssyndrom?

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Amanda Lönneborg; [2022]
    Nyckelord :;

    Sammanfattning : Tvångssyndrom eller obsessive-compulsive disorder (OCD) är en kronisk sjukdom vilket präglas av tvångstankar och tvångshandlingar som baseras på ångest. Tvångssyndrom är en produkt av abnormiteter i kortiko-striato-talamo-kortikala (CSTC)-kretsar vilket är associerat med förändring av transmittorsubstanserna serotonin, dopamin, glutamat och γ-aminosmörsyra. LÄS MER

  4. 4. Radiofrequency-Induced Heating of a Deep Brain Stimulator Lead inside TEM Cells and inside a 3T MR-Scanner

    Master-uppsats, Umeå universitet/Radiofysik

    Författare :Haider Shaban; [2022]
    Nyckelord :Medical Physics; MRI; ;

    Sammanfattning : The use of non-ionizing radiation in the magnetic resonance imaging (MRI) made it a safer diagnostic technique in comparison to the X-ray imaging method. MRI can also produce soft tissue images with a very high contrast without contrast agent which is another advantage that made MRI an important imaging technique for studying the mechanism of the deep brain stimulation (DBS) and for targeting the desired regions in the brain that should be stimulated. LÄS MER

  5. 5. Sex-differences in reported adverse side-effects caused by Deep Brain Stimulation therapy in the subthalamic nucleus

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Lucas Werner; [2021]
    Nyckelord :Deep brain stimulation; subthalamic nucleus; sex-differences; STN-DBS; Parkinson s disease;

    Sammanfattning : Parkinson’s disease is a common neurological disease which will progressively damagedopaminergic neurons in the brain. Later stages of the disease will result in death of theneurons. The diagnosis is often made with respect to the motor symptoms, which includetremors, bradykinesia, and rigidity. LÄS MER