Sökning: "llps"

Visar resultat 1 - 5 av 6 uppsatser innehållade ordet llps.

  1. 1. Investigation on Liquid-Liquid Phase Separation in Immunoglobulin G Solutions

    Kandidat-uppsats, Stockholms universitet/Fysikum

    Författare :Lovisa Jansson; [2023]
    Nyckelord :Protein; Liquid-Liquid Phase Separation; Microscopy; Light Scattering;

    Sammanfattning : Liquid-liquid phase separation (LLPS) is an important phenomenon in soft condensed matter that explains many properties of membraneless organelles in living cells. The research on this topic is, therefore, a field with a wide range of applications such as biopharmacy and biomaterials. LÄS MER

  3. 2. Competition between Phase Separation and Micellization in a Coarse-Grained Protein Model with Two Components

    Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Fangxuan Lyu; [2022]
    Nyckelord :Physics and Astronomy;

    Sammanfattning : Intrinsically disordered proteins (IDPs) are widely believed to play a key role in the for- mation of intracellular biomolecular condensates through liquid-liquid phase separation (LLPS). Furthermore, it has been shown in vitro that several IDPs are able to phase sepa- rate on their own. LÄS MER

  4. 3. Phase behavior of mixtures of polyampholytic proteins and RNA: a toy model study

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Sonny Nilsson; [2022]
    Nyckelord :llps; biomolecular condensates; polyampholyte; polymer; demixing; mixing; RNA; protein; IDP; phase transition; aggregation; charge decoration; mixing parameter; flory-huggin; step potential; metropolis hasting; sv; Physics and Astronomy;

    Sammanfattning : Biomolecular condensates are aggregates formed from liquid-liquid phase separation through the interactions between nucleic acids and multivalent proteins. These condensates are essential for many biochemical processes inside the cell. LÄS MER

  5. 4. Investigation on liquid liquid phase separation of lysozyme by dynamic light scattering

    Master-uppsats, Stockholms universitet/Fysikum

    Författare :Hanna-Friederike Poggemann; [2021]
    Nyckelord :Protein; protein dynamics; Liquid-liquid phase separation; DLS;

    Sammanfattning : The liquid-liquid phase separation (LLPS) of biomolecules is a phenomenon which received a lot of attention in the last years because it is not only related to theformation of membraneless organelles but also to neurodegenerative diseases. Lysozyme is a globular protein that undergoes LLPS in a buffer salt system andfor that it is well investigated with several techniques like microscopy, dynamic lightscattering (DLS) or small-angle X-ray scattering. LÄS MER

  7. 5. Liquid-Liquid Phase Separation of HP Lattice Proteins: A Finite-Size Scaling Analysis

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Markus Ernstsson; [2020]
    Nyckelord :LLPS; Finite-size scaling; Protein droplets; Biomolecular condensates; Monte Carlo; Lattice gas; Multicanonical simulations; Phase diagram; Physics and Astronomy;

    Sammanfattning : Biomolecular condensates are dense droplets of proteins and nucleic acids inside living cells that form through a liquid-liquid phase separation (LLPS) process, in which intrinsically disordered proteins (IDPs) often play an important role. Furthermore, it has been shown that several of these IDPs can form similar droplets on their own. LÄS MER