Sökning: "differential protein expression analysis"

Visar resultat 1 - 5 av 11 uppsatser innehållade orden differential protein expression analysis.

  1. 1. BAYESIAN HIERARCHICAL LINEAR MODELS FOR DIFFERENTIAL PROTEIN EXPRESSION ANALYSIS

    Master-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Siri Voghera; [2023]
    Nyckelord :Bayesian hierarchical modeling; differential protein expression analysis; proteomics;

    Sammanfattning : It is evident that the study of proteins is crucial for a deeper understanding of how drug treatments affect the body. However, differential protein expression analysis, which can be described as the method of finding which proteins are affected by a treatment, faces some major challenges. LÄS MER

  3. 2. Differential expression and function of fubl-1 gene isoforms in C. elegans

    Kandidat-uppsats, Uppsala universitet/Molekylärbiologi; Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Joel Pålsson; [2022]
    Nyckelord :isoform; gene expression; C elegans; protein; alternative splicing; isoformer; genuttryck; C elegans; protein; alternativ splicing;

    Sammanfattning : Alternative splicing is the process of producing a variety of transcripts from one and the same gene. This adds further possible variability to gene expression and can in theory mean that one protein coding gene can produce multiple proteins with potentially different functions. LÄS MER

  4. 3. Optimal peptide quantification via machine learning enhanced fragment ion ranking in DIA-MS proteomics

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Lina Lu; [2022]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : In a standard mass spectrometry workflow, acquired mass spectra are searched against a library of peptides to extract peptide spectra matches (PSMs). Peptides are normally quantified by aggregating the intensities of fragment ions extracted from MS/MS spectra. LÄS MER

  5. 4. Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator

    Master-uppsats, Uppsala universitet/Institutionen för kemi - BMC

    Författare :Carita Hammar; [2022]
    Nyckelord :;

    Sammanfattning : The bacterium Saccharopolyspora erythraea is utilized to produce the widely used antibiotic erythromycin. With the increasing problem of antibiotic resistance, the development of derivatives of the drug is of great importance. To produce antibiotics biosynthetically, it is crucial to understand the metabolic pathways utilized by the bacterium. LÄS MER

  7. 5. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Ojong Tabi Ojong Besong; [2021]
    Nyckelord :;

    Sammanfattning : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. LÄS MER