Sökning: "NLRP3 inflammasome"
Visar resultat 1 - 5 av 18 uppsatser innehållade orden NLRP3 inflammasome.
1. The effect of GSK-3 inhibitor SB216763 on the expression and secretion of IL-8 in THP-1 ASC GFP macrophages cells
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammation is a part of the innate immune system. It protects the body against foreign invaders such as bacteria and viruses. Inflammation helps to restore the body by removing harmful stimuli and starting the healing process. LÄS MER
2. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. LÄS MER
3. Factors and mechanisms associating the mobilisation of Ca2+ with the activation of the NLRP3 inflammasome : A systematic review
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammasomes are multiprotein complexes that play a critical role in the regulation of inflammation and the inflammatory responses against pathogens. NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3) is among the molecules involved in the homonymous and well-studied NLRP3 inflammasome that accounts for the release of the pro-inflammatory cytokines interleukin (IL) 1-β and 18. LÄS MER
4. GSK-3 and ROS (reactive oxygen species) inhibition modulate Vimentin expression
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : When exposed to pathogenic stress, cellular processes and survival are dependent on cytoskeletal proteins for structure and organisation of the cell to adapt and maintain homeostasis during inflammation. Vimentin is type III cytoskeletal protein, with an extensive cytoplasmic meshwork, across the cell and regulate the cell structure and cellular space and expressed strongly under tumorigenic events. LÄS MER
5. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. LÄS MER
