Sökning: "Oligonucleotide therapeutics"

Hittade 2 uppsatser innehållade orden Oligonucleotide therapeutics.

1. 1. Non-coding RNAs as therapeutic agents : The future of therapy

   Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
   Nyckelord :Non-coding RNA; Oligonucleotide therapeutics;

   Sammanfattning : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. LÄS MER

3. 2. Development of Peptide Nucleic Acid Based Artificial Ribonucleases, PNAzymes

   Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling

   Författare :Sara Andersson; [2010]
   Nyckelord :;

   Sammanfattning : Since mRNA plays such a vital role in the transfer of genetic code from DNA to proteins, approaches involving interference with mRNA are of great interest for use in therapeutics. Amongst these, peptide nucleic acid based nuclease systems (PNAzymes) are being developed for in vivo gene silencing in future. LÄS MER