Synthesis and characterization of half-sandwich complexes with salicylaldimine ligand derivatives

Sammanfattning: New half-sandwich complexes of pentamethylcyclopentadienyl-rhodium, iridium, and p-cymene-ruthenium have been synthesized and characterized. All metal complexes contain ligands based on a 4-chloroquinoline framework analogous to the antimalarial drug chloroquine. The first reaction in the preparation of a new ligand is a nucleophilic substitution at the chloro position of 4-chloro-7-fluoroquinoline by a Schiff base condensation. The salicylaldimine ligand derivatives are synthesized by a Schiff base condensation from N1-(7-fluoroquinolin-4-yl)ethane-1,2-diamine and determined 2-hydroxy-benzaldehydes in ethanol which leads to the formation of HLSAL(H), HLSAL(F), HLSAL(Cl), HLSAL(Br), and HLSAL(I) ligands. Furthermore, these ligands will then be used to coordinate with the metal dimers [Ir(Cp')Cl2]2, [Rh(Cp')Cl2]2, and [Ru(p-cymene)Cl2]2 to synthesize the different metal complexes. Due to the startingmaterial 4-chloro-7-fluoroquinoline not reacting with various ligands along with the metal complexes, no metal complexes could be obtained. Instead, another starting material was utilized for further examination.