Sökning: "Elisabeth Jirström"
Hittade 1 uppsats innehållade orden Elisabeth Jirström.
1. Towards Identifying Pharmacodynamic Blood Biomarkers of MAP3K12 Inhibition
Master-uppsats, Lunds universitet/Tillämpad biokemiSammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons in the brain and spinal cord, for which there is no cure. Activation of the stress-induced c-Jun N-terminal kinase (JNK) signaling pathway, a critical mediator of neuronal apoptosis and axon degeneration, is evident in ALS and is therefore considered a potential target to prevent neurodegeneration. LÄS MER
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