Sökning: "Epigenetic regulation"

Visar resultat 1 - 5 av 21 uppsatser innehållade orden Epigenetic regulation.

  1. 1. Identification of epigenetic biomarkers associated with the development of diabetic kidney disease in individuals with type 2 diabetes: a nested cohort study

    Master-uppsats, Lunds universitet/Socialmedicin och global hälsa

    Författare :Marian Paiva Marchiori; [2023]
    Nyckelord :Medicine and Health Sciences;

    Sammanfattning : Introduction. Type 2 diabetes (T2D) is the most common type of diabetes, and it can cause complications such as diabetic kidney disease (DKD), the main cause of end-stage renal disease worldwide. There is an urgent need to develop new biomarkers that would improve DKD’s risk prediction in patients with T2D. LÄS MER

  3. 2. Epigenetic and transcriptional effects of full-length LINE-1 retrotransposons in human neural progenitor cells

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Ninoslav Pandiloski; [2021]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. LÄS MER

  4. 3. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Ojong Tabi Ojong Besong; [2021]
    Nyckelord :;

    Sammanfattning : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. LÄS MER

  5. 4. Characterization of DNA Methylation in Giardia intestinalis

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Hassanat Agongo; [2021]
    Nyckelord :;

    Sammanfattning : Abstract G. intestinalis is an intestinal protozoan parasite that causes 180 million symptomatic diarrheacases (giardiasis) and more than 0.5 billion asymptomatic infections per year. Symptomaticinfections are usually treated with metronidazole (Flagyl). LÄS MER

  7. 5. Epigenetic Regulation of Mitochondrial DNA

    Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Jennie Johansson; [2020]
    Nyckelord :Acetylation; Epigenetics; Heteroplasmy; Methylation; Mitochondrial haplotype; Mitochondrion; Non coding RNA; Phosphorylation;

    Sammanfattning : This mini-review investigates and compiles the latest knowledge regarding epigenetic changes on the mammalian mitochondrial DNA and its proteins. Methylation of the DNA, acetylation of the proteins and silencing of genes by short non-coding RNAs are the main epigenetic changes known today to affect mitochondrial DNA, mostly leading to repression. LÄS MER