Sökning: "Pluripotent stem cells"

Visar resultat 1 - 5 av 15 uppsatser innehållade orden Pluripotent stem cells.

  1. 1. Review of magnetic bead surface markers for stem cell separation : Literature study for MAGic Bioprocessing

    Kandidat-uppsats, Uppsala universitet/Institutionen för materialvetenskap

    Författare :Gustav Holmberg; Adrian Svensson; Erik Bergström; Leo Westerberg; Watthachak Wijitchakhorn; [2022]
    Nyckelord :Magnetic bead; stem cell; surface antigen; immunotherapy; regenerative medicine; market analysis; separation technique;

    Sammanfattning : Stem cell therapy and transplantation is a quickly evolving field with many clinical applications. However, several problems need to be overcome before they can be applied on an allogenic scale, and among them is ensuring of the purity of the applied differentiated stem cell culture. LÄS MER

  3. 2. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Claudia De Guidi; [2021]
    Nyckelord :;

    Sammanfattning : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). LÄS MER

  4. 3. Derivation and characterization of pacemaker cells from human induced pluripotent stem cells for investigation of cardiotoxicity

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Dorottya Markó; [2021]
    Nyckelord :stem cell; cardiomyocyte; differentiation;

    Sammanfattning : .... LÄS MER

  5. 4. Study of up-regulated genes in gene clusters during formation of mature hepatocytes from human induced pluripotent stem cells to identify transcription factors and mirnas

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Suraj Thomas Alexander; [2021]
    Nyckelord :;

    Sammanfattning : The multifunctional purpose of hepatocytes, the functional liver cells within the metabolic, endocrine and secretory functions highlights key importance in emphasizing the research and treatment methods that utilize these cells. Forming 80% of the liver's cells, hepatocytes are involved in many of the primary functions of the liver including the delivery of immune response against pathogens and aiding in the detoxification of drugs. LÄS MER

  7. 5. Explorative bioinformatic analysis of cardiomyocytes in 2D &3D in vitro culture system

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Sruthy Janardanan; [2021]
    Nyckelord :Cardiomyocytes; Pluripotent stem cells; 2D; 3D; differentially expressed genes; Hub nodes; Hub-Bottleneck nodes;

    Sammanfattning : The in vitro cell culture models of human pluripotent stem cells (hPSC)-derived cardiomyocytes (CMs) have gained a predominant value in the field of drug discovery and is considered an attractive tool for cardiovascular disease modellings. However, despite several reports of different protocols for the hPSC-differentiation into CMs, the development of an efficient, controlled and reproducible 3D differentiation remains challenging. LÄS MER