Sökning: "TCA-cycle"
Visar resultat 1 - 5 av 6 uppsatser innehållade ordet TCA-cycle.
1. Measuring bacterial metabolism and antibioticsusceptibility : using silicon nanowire field-effect transistor.
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Fasta tillståndets elektronikSammanfattning : Antimicrobial resistance is considered by many prominent researcher and scientist as a profound global health crisis that us humans must face in the next decade. It is threatening the effectiveness of these once-reliable weapons against bacterial infections and leaving us susceptible to pathogenic agents. LÄS MER
2. Impact of PFAS exposure on the fecal metabolome
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : The human gut microbiota plays a crucial role in human health and therefore imbalances in gut microbiota functioning can lead to the development of metabolic disorders. Short-chain fatty acids (SCFA), tricarboxylic acid (TCA) cycle metabolites, bile acids (BA) and other metabolites are the essential compounds for the metabolome. LÄS MER
3. Impact of polychlorinated biphenyl- and organochlorine pesticide exposure on faecal metabolome
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : The gut microbiota plays a major part in maintaining the health of a human host. Countless of crucial functions in the body, including immune responses, cell signaling and energy metabolism to name a few, are conducted by the gut microbiota and its metabolites. LÄS MER
4. Implementation of a straightforward derivatizationmethod for the simultaneous analysis of short chainfatty acids and tricarboxylic acid cycle metabolitesby LC-qToF-MS.
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : Short-chain fatty acids (SCFAs) and the tricarboxylic acid (TCA) cycle metabolites aresmall hydrophilic compounds that play crucial roles in biological species ranging fromenergy metabolism, immune homeostasis to cellular signalling. There is a need for reliableand precise quantification of these metabolites in biological matrices as they can providecrucial information of metabolic status and potentially be used as diagnostic biomarkersfor different pathological and physiological conditions. LÄS MER
5. Metabolic engineering of Escherichia coli for direct production of 4-hydroxybutyrate from glucose
Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)Sammanfattning : Growing concerns of the negative effects on the environment and dependency of fossil fuelsare major driving forces for finding novel sustainable production pathways for plastic.Metabolic engineering has emerged as a powerful tool to enable microorganisms to producenon-native metabolites. LÄS MER