Sökning: "reporter gene assay"

Visar resultat 1 - 5 av 11 uppsatser innehållade orden reporter gene assay.

  1. 1. The regulatory action of NFIB on the liver specific gene transcription of CYP2D6, a reporter gene assay study

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för integrativ medicinsk biologi (IMB)

    Författare :Jennifer Nilsson; [2022]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 2. Using effect-based methods to evaluate the presence of bioactive compounds in food contact materials made of paper and cardboard

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Mimmi Wänn; [2021]
    Nyckelord :Food toxicology; food contact materials; cell-based in vitro bioanalytical methods; cytotoxicity; reporter gene assay; bioactivity; bioassays; paper and cardboad;

    Sammanfattning : Food contact materials are materials that are intended to come into contact with food, and we are exposed to different types of chemicals that exist in the packages on a daily basis. In this study, a battery of effect‑based in vitro cellular bioassays was used to evaluate the presence of bioactive compounds in commonly used food contact materials made of paper and cardboard, retrieved from the Swedish market. LÄS MER

  4. 3. Development of a reporter gene assay on an automated platform

    Master-uppsats, Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Författare :Fanny Redin; [2021]
    Nyckelord :Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. LÄS MER

  5. 4. TPA and other small molecules can regulate the lategene expression in Human Papillomavirus (HPV-16)

    Kandidat-uppsats, Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Författare :Erica Jissbacke; [2015]
    Nyckelord :BELMCAT; CAT assay ELISA ; Cell culture; Cervical cancer; Transfection;

    Sammanfattning : Cervical cancer is almost exclusively caused by the HPV virus, whit HPV 16 and 18 involved in the majority of cases. The HPV virus can be divided into high risk and low risk types, where the high risk types are most associated with cancer. HPV is spread by sexual skin to skin contact, many people get infected without getting cervical cancer. LÄS MER

  7. 5. Effekten av sulforafan på genuttrycket av breast cancer resistance protein i MCF-7 celler

    Uppsats för yrkesexamina på avancerad nivå, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Karolina Sjöberg; [2015]
    Nyckelord :sulforafan; breast cancer resistance protein; BCRP; nuclear factor E2-related factor-2; Nrf2; MCF-7; bröstcancerceller; mjölk; sulforaphane; breast cancer resistance protein; breast cancer cells; milk;

    Sammanfattning : Sulforafan är en isothiocyanat-förening som finns i stora mängder i olika kålväxter. Sulforafan har setts ha en kemopreventiv inverkan bland annat genom att inducera fas II-enzymer styrda av transkriptionsfaktorn nuclear factor E2-related factor-2 (Nrf2). LÄS MER