Sökning: "sialic acid"

Visar resultat 1 - 5 av 11 uppsatser innehållade orden sialic acid.

  1. 1. Finding the Sweet Spot

    Master-uppsats, Göteborgs universitet/Institutionen för data- och informationsteknik

    Författare :VIKTORIA KARLSSON; [2022-06-29]
    Nyckelord :Glycans; glycome; cancer; tumor; machine learning; bioinformatics; data science; thesis;

    Sammanfattning : Complex carbohydrates, or glycans, are involved in cancer progression and could thereby serve as diagnostic markers as well as therapeutic targets. However, new research is required to determine which glycan motifs are universal signatures of tumor environments. LÄS MER

  3. 2. Exploring Regioselective 5N-acylation of Neuraminic acid

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Simon Hans Lilje; [2022]
    Nyckelord :acylation; amide; antibacterial drugs; regioselective deprotection; sialic acid; organic chemistry; Chemistry;

    Sammanfattning : In this project, a regioselective method to deprotect and acylate the amide on C5 of sialic acid is explored. Sialic acid is one of the most complex monosaccharides and is an important ligand in many higher organisms in intercellular cell communication. The most prominent example is related to the immune system. LÄS MER

  4. 3. Tuning the crosslinking chemistry for self-healable mucin hydrogel synthesis and application

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Francesca Pacella; [2020]
    Nyckelord :Mucin; Hydrogel; Click-chemistry; Characterization; Self-healing; Injectable; Hydrogeler; Mucin; självhelande;

    Sammanfattning : Immune-orchestrating biomaterials that precisely modulate the immune reac-tion to the host could lead the way for improving the implantation outcomein the transplantation field, in comparison to passive biomaterials. The lab-oratory of Dr. LÄS MER

  5. 4. Synthesis of divalent sialic acid conjugates targeting coxsackievirus A24 variant

    Kandidat-uppsats, Umeå universitet/Kemiska institutionen

    Författare :Carl Larsson; [2019]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Synthesis of the sialic acid 9-C derivative with an amino group replacing the OH-group.

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Hanna Malmquist; [2018]
    Nyckelord :organic chemistry; sialic acids; antibiotics; organic synthesis; organisk kemi; Chemistry;

    Sammanfattning : Almost everyone is aware of the big problem with increasing antibiotic resistance among bacteria and the importance and need of developing new antibiotics. This bachelor thesis is a part of one such project with the aim to find new possible antibiotics. A promising candidate is a derivative of the sialic acids. LÄS MER