Sökning: "Anna Ivert Nordén"

Hittade 2 uppsatser innehållade orden Anna Ivert Nordén.

1. 1. Development of specific host cell protein assays

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Anna Ivert Nordén; [2023]
   Nyckelord :Gyrolab; Immunoassay; HCP;

   Sammanfattning : The manufacturing and the development of biotherapeutic drugs involves the expression of biotherapeutic proteins in a host cell expression system followed by a purification process. Bioanalytical methods to measure impurities such as host cell proteins (HCPs) are needed to obtain a robust process and a safe drug according to regulatory requirements. LÄS MER

3. 2. Immunoassays or LC-MS/MS? : A Comparison Revealing the Properties of Modern Methods for Insulin, Pro-insulin, C-peptide and Glucagon Quantification

   Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Ruta Upite; Susanna Wärmegård; Casper Tiger; Anna Ivert Nordén; Temis Martinez; Viktor Umenius; [2019]
   Nyckelord :Biomarker quantification; insulin; pro-insulin; c-peptide; glucagons; immunoassays; LC-MS MS;

   Sammanfattning : The purpose of this report is to compare seven different methods for biomarker detection and quantification based on previously published papers. The methods investigated are ELISA, LC-MS/MS, UPLC-MS/MS, LC-IM/MS, IA-LC-MS/MS, MSIA-HR/AM, HTRF and AlphaLISA ® . LÄS MER