Sökning: "Simulation-estimation study"
Hittade 1 uppsats innehållade orden Simulation-estimation study.
1. Critical evaluation of methods for estimation of increase in systemic drug exposure for renally impaired patients
Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskapSammanfattning : Introduction: The effect of renal impairment (RI) on systemic exposure is assessed in phase I with RI studies and/or in phase III with population pharmacokinetic analysis. Regulatory review has indicated that the estimated effect of RI from the two methods may differ. LÄS MER
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