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Visar resultat 1 - 5 av 8 uppsatser som matchar ovanstående sökkriterier.
1. Expression and purification of pyruvate transporting human mitochondrial pyruvate carrier (MPC) protein complex for structural studies
Magister-uppsats, Lunds universitet/Examensarbeten i molekylärbiologiSammanfattning : Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. LÄS MER
2. The role of salt inducible kinases in the regulation of the mammalian target of rapamycin pathway in adipocytes
Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologiSammanfattning : Salt inducible kinase 2 (SIK2) is found abundantly in adipose tissue and may have a role in the development of diabetes. SIK2 is downregulated in insulin-resistant and obese individuals, thereby providing a new potential target for therapeutic solutions. LÄS MER
3. Effects of Insulin and Glucose Stimulation on the Anti-Viral Response in Bronchial Epithelial Cells
Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologiSammanfattning : Asthma exacerbation is among the leading causes of mortality and morbidity. Bronchial epithelial cells (BECs) are of interest because they represent not only a physical barrier against infections, but also a biological barrier between the inhaled agents, such as allergens, and the immune system. LÄS MER
4. Kloning, överuttryck och upprening av växtakvaporinet AtSIP1;1 i Escherichia coli
Kandidat-uppsats, Lunds universitet/Examensarbeten i molekylärbiologiSammanfattning : Heterologous overexpression of proteins signifies that the encoding gene of a protein in one organism is expressed in another host organism that normally does not have that gene in its genome. In basic biochemical research, this is an important method for studying various protein functions such as activity and interactions in biological processes, as well as obtaining sufficient amounts to determine protein structures. LÄS MER
5. THE NEURODEGENERATION PROCESS IN THE STRIATUM OF MICE EXPOSED TO OBESOGENIC DIETS
Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologiSammanfattning : Obesity and diabetes are known to impact brain function and alter metabolism. Studies in rodents show that consumption of high fat and high sugar diets lead to brain dysfunction affecting memory and cognition, and increases risk of cerebro-vascular and neurodegenerative disorders. LÄS MER
