Sökning: "CCR5"

Hittade 5 uppsatser innehållade ordet CCR5.

  1. 1. Variations in the CCR5-gene and its effect on CAE, in goat

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Hanna Tiilikainen; [2021]
    Nyckelord :CCR5; caprine arthritis encephalitis; goat; SRLV; small ruminant lentiviruses;

    Sammanfattning : Caprine Arthritis Encephalitis (CAE) is a disease negatively affecting goats, around the world. A mutation on the CCR5-gene has showed an increase in viral load. CAE is a lentivirus that affects the monocytes/macrophages. It is a disease similar to HIV in humans and the animal can be a carrier for months to years before symptoms start to show. LÄS MER

  3. 2. Resistens mot Caprin artrit encefalit och genetisk variation i αS1-kasein genen (CSN1S1) hos svenska getter

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Sofie Gunnarsson; [2020]
    Nyckelord :Kaprin artrit encefalit; maedi visna; virus; sjukdomsförekomst; CCR5; CSN1S1; kasein; αS1-kasein; osttillverkning; kopplingsojämvikt; genetisk variation; allelfrekvens;

    Sammanfattning : Caprin artrit encefalit (CAE) och låga koncentrationer av αS1-kasein (αS1-kn) i mjölken är två problemområden inom den svenska getproduktionen. Caprin artrit encefalit är en virussjukdom som liknar humant immunbristvirus (HIV) hos människa och maedi visna hos får. LÄS MER

  4. 3. HIV-1 resistensgivande genetiska variationer rörande CD4+ T-lymfocyteroch induktion av resistens : En systematisk litteraturstudieom rådande kunskaper och potentiella lösningartill en global kris

    Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Ricky Mantea; [2019]
    Nyckelord :;

    Sammanfattning : Background.HIV-1 is one of mankind’s largestpandemics and is associated with great social stigma. There are effective antiretroviral medications capable of halting disease progress but no definitive cure. However, a few individuals have been shown to be resistant to HIV-1. LÄS MER

  5. 4. Development of a label-free biosensor method for the identification of sticky compounds which disturb GPCR-assays

    Master-uppsats, Institutionen för biologisk grundutbildning

    Författare :Hamno Mohammed Kader; [2013]
    Nyckelord :Surface plasmon resonance SPR ; biosensor; Biacore; G-protein-coupled receptors GPCRs ; Low molecular weight LMW compounds; C-C chemokine receptor type 5 CCR5 ; acid-sensing ion channel 1a ASIC1a ; Thrombin; Carbonic Anhydrase II CA II ; P38α MAP kinase.;

    Sammanfattning : It is widely known that early estimates about the binding properties of drug candidates are important in the drug discovery process. Surface plasmon resonance (SPR) biosensors have become a standard tool for characterizing interactions between a great variety of biomolecules and it offers a unique opportunity to study binding activity. LÄS MER

  7. 5. Effects of different conditions of HIV-1 on plasmacytoid dendritic cells in maturation and function

    Kandidat-uppsats, Institutionen för fysik, kemi och biologi

    Författare :Susana Häggqvist; [2008]
    Nyckelord :Plasmacytoid dendritic cells; Interferon-α; HIV-1; complement and immune complexed opsonized.;

    Sammanfattning : Plasmacytoid dendritic cells (PDCs) are one cellular target of HIV-1 and respond to the virus by producing type I interferons and chemokines. PDCs exposed to HIV-1 strongly upregulate the expression of maturation markers such as CD83, CD80, CD86 and CCR7, which will turn them into professional antigen presenting cells with the ability to stimulate naïve CD4+T cells. LÄS MER