Sökning: "Hydrogels"

Visar resultat 21 - 25 av 36 uppsatser innehållade ordet Hydrogels.

1. 21. Optimization of Acidic Degradation of Hyaluronic Acid using Design of Experiments

   Master-uppsats, Linköpings universitet/Teknisk biologi

   Författare :Emma Sandqvist Wedin; [2019]
   Nyckelord :Hyaluronic Acid; Molecular Weight; Acidic Degradation; Heterogeneous Degradation; Robustness Testing; Degradation Constant; Design of Experiments; Degradation; DoE;

   Sammanfattning : Hyaluronic acid (HA) is an unbranched polysaccharide consisting of the repeating disaccharide unit β(1→4)-GlcA-β(1→3)-GlcNAc and is a naturally occurring biopolymer in bacteria and vertebras. HA is predominantly found in the extracellular matrix (ECM) and the in vivo function of HA can vary depending on molecular weight (Mw) for instance high Mw HA is reported to be anti-angiogenic while low Mw HA induces angiogenesis. LÄS MER

3. 22. Endeavors toward Novel Cochlear Implants from Stretchable Printed Circuit Board Technology

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrosystemteknik

   Författare :Rickard Viik; [2019]
   Nyckelord :novel; cochlear; implant; electrode array; electrode; stretchable; soft; electronics; pdms; polydimethylsiloxane; liquid; alloy; galinstan; hearing aid;

   Sammanfattning : Profound sensorineural hearing loss is at the present time a major worldwide health concern, affecting over 5% of the worlds' population. Through cochlear implants (CI), treatment of sensorineural hearing loss now offers the possibility to restore hearing function through electrical stimulation of auditory nerves. LÄS MER

4. 23. Analysis of hydrogels for immobilisation of hepatocytes (HepG2) in 3D cell culturing systems

   Master-uppsats, Linköpings universitet/Teknisk biologi

   Författare :Elisabeth Westergren; [2018]
   Nyckelord :Hydrogel; Hepatocyte; Tuneable; PEG-peptide; 3D cell culture;

   Sammanfattning : In pharmaceutical development cell cultures are used as in vitro models to evaluate the function of drug candidates. In such research it is vital to have models that resemble the in vivo environment to get reliable results. LÄS MER

5. 24. One Bead One Compound Screening for Cyclic Peptide Binding Partners

   Master-uppsats, Linköpings universitet/Molekylär fysik

   Författare :Johanna Utterström; [2018]
   Nyckelord :Cyclic peptides; SPPS-synthesis; OBOC library; SAAP-screening; PED MS sequencing; SPR; dimerization;

   Sammanfattning : In recent years a significant research focus has been on the development of biomimicking three-dimensional substrates for cell culturing. Hydrogels mimicking the extracellular matrix is a well-suited scaffold for this purpose and there are many different ways these can be cross-linked to retain their shape. LÄS MER

7. 25. Injectable, in situ crosslinked hydrogels by Fenton’s Reagent (Fe (II) & H2O2) for corneal perforations

   Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Författare :Mehmet Nizamoglu; [2018]
   Nyckelord :;

   Sammanfattning : Corneal perforations are medical emergencies in which the cornea is partially or completely ruptured, resulting in the loss of stability of the whole eye. Such situations can be caused by bacterial or fungal keratitis, autoimmune, or ocular-surface related disorders. Corneal perforations, if left untreated, can cause partial or total blindness. LÄS MER