Sökning: "MEK inhibitor"

Hittade 2 uppsatser innehållade orden MEK inhibitor.

1. 1. Validation of a 3D culture model for toxicity studies in malignant and non-cancerous cells

   Master-uppsats, Lunds universitet/Institutionen för immunteknologi

   Författare :Kajsa Andreasson Dahlgren; [2021]
   Nyckelord :Dose-response; potency; in vitro; 2D model; 3D model; cancer; MEK inhibitor; trametinib; A549; LL47; Western blot; Biology and Life Sciences;

   Sammanfattning : Cancer is a widespread and commonly fatal disease in constant need of new treatments. Traditionally, new pharmaceuticals have been tested in 2D models. This is not ideal, as 2D environments do not reflect the in vivo milieu of the cells. LÄS MER

3. 2. Enhanced Cellular Uptake of Virus by Increased Expression Levels of the Coxsackie-and Adenovirus Receptor

   L3-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Författare :Lina Lindström; [2005]
   Nyckelord :oncolytic viruses; CAR;

   Sammanfattning : Replication–selective oncolytic adenoviruses have shown great promise as novel anti-cancer agents. These mutant viruses act through different mechanisms than traditional anti-cancer therapies and consequently do not develop cross-resistance with these drugs. LÄS MER