Sökning: "copy number polymorphisms"

Hittade 3 uppsatser innehållade orden copy number polymorphisms.

1. 1. Characterising copy number polymorphisms using next generation sequencing data

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

   Författare :Zhiwei Li; [2019]
   Nyckelord :structural variations; copy number variations; copy number polymorphisms; next generation sequencing; The Northern Sweden Population Health Study; Genome-wide association study;

   Sammanfattning : We developed a pipeline to identify the copy number polymorphisms (CNPs) in the Northern Swedish population using whole genome sequencing (WGS) data. Two different methodologies were applied to discover CNPs in more than 1,000 individuals. LÄS MER

3. 2. Molecular analysis of dog and wolf genomic DNA to explore integration polymorphisms of Canine Endogenous Retroviruses, CfERV

   Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

   Författare :MohammadReza Mirzazadeh; [2012]
   Nyckelord :Endogenous Retrovirus ERV ; Canine Endogenous Retrovirus CfERV ; germ line; Vertical transmission; Polymorphism; Copy Number Variation CNV ;

   Sammanfattning : Endogenous retroviruses (ERVs) are found in all examined vertebrate genomes. Different mammals have been reported to contain different amounts of ERVs. For example, in the dog genome 0.15% of sequences are derived from retroviruses. LÄS MER

4. 3. Copy number variations as potential biomarkers for disease development in Breast Cancer

   Master-uppsats, SLU/Dept. of Microbiology

   Författare :Reddy Prakash Kancherla; [2011]
   Nyckelord :Breast cancer; Copy number variation; IFNAR1; VNTR;

   Sammanfattning : Breast cancer is second foremost cause of deaths in women caused by malignant tumor.Comparing genetic profiles of cells surrounding the tumor and blood from same patient may reveal de‐novo somatic aberrations that may predispose normal cells to cancer cells. LÄS MER