Sökning: "disulphide bonds substitution"
Hittade 1 uppsats innehållade orden disulphide bonds substitution.
1. Substitution of disulphide bonds to hydrophobic amino acids in BACE1
Master-uppsats, Institutionen för fysik, kemi och biologiSammanfattning : The study and understanding of Alzheimer’s disease on protein level is fundamentally important in the search for its treatment and there is a demand for proteins that can be used together with candidate drugs in crystallography trials. The refolding time reaching up to three weeks for beta-site APP cleaving enzyme 1 (BACE1), the proposed disease-generating protein, is presently not optimal and new protein constructs are needed. LÄS MER
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