Sökning: "Agni Karolina Tsiatsiou"

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  1. 1. Ligand-stimulated cleavage of PDGFR-beta

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Agni Karolina Tsiatsiou; [2023]
    Nyckelord :;

    Sammanfattning : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. LÄS MER