Sökning: "Dicer"

Hittade 4 uppsatser innehållade ordet Dicer.

  1. 1. A novel Adenoviral miRNA, a candidate for development of a novel gene therapy startegy

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Benjamin Danish; [2019]
    Nyckelord :A novel Adenoviral miRNA;

    Sammanfattning : In 2017, a novel miRNA was found at the MLTU-region of adenoviral genome, termed as MLP-TSS-sRNA. This current study started with performing a series of mutations in the MLP-TSS-sRNA in order to investigate how the MLP-TSS-sRNA as a single stranded small RNA was protected from rapid RNA degradation in transfected cells (in vivo). LÄS MER

  2. 2. Lactobacilli Suppress Gene Expression of Key Proteins Involved in miRNA Biogenesis in HT29 and VK2/E6E7 Cells

    Magister-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Annette Jacobsen; [2013]
    Nyckelord :Argonaute; Dicer; Drosha;

    Sammanfattning : It has previously been demonstrated that lactic acid bacteria are able to influence the innate immune response of host cells. One way this can be achieved is through modulation of inflammatory cascades initiated by pattern recognition elements such as toll-like receptors. LÄS MER

  3. 3. The role and genetic control of non-coding RNAs in bacterial infection

    Master-uppsats, SLU/Dept. of Molecular Biology (until 131231)

    Författare :Jonas Åkerblom; [2010]
    Nyckelord :Dictyostelium discoideum; non-coding RNA; RNAi; Legionella pneumophila; bacterial infection; miRNA; siRNA; promoter;

    Sammanfattning : Promoters are genetic elements that facilitate the transcription of a gene and they have been found in front of non-coding RNA (ncRNA) genes in different organ-isms, e.g. the model plant Arabidopsis thaliana. LÄS MER

  4. 4. mRNA and natural endogenous antisense RNA in Dictyostelium discoideum

    L3-uppsats, SLU/Dept. of Molecular Biosciences

    Författare :Louise Andersson; [2006]
    Nyckelord :RNAi; mRNA; antisense RNA; Dictyostelium discoideum;

    Sammanfattning : The aim of this Master's Thesis was to investigate the presence and regulation of RNAi in the model organism Dictyostelium discoideum. The background for the project is a cDNA library representing 18-25nt RNAs (9000 clones) from Dictyostelium discoideum that recently was constructed. LÄS MER