Sökning: "Radioligand binding assay"

Hittade 1 uppsats innehållade orden Radioligand binding assay.

  1. 1. Characterization of the binding of the novel compound GT-002 to GABAA receptors in the mammalian brain : Development and validation of a radioligand binding assay. A comparative study to Flumazenil

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Zemowska Emelie; [2017]
    Nyckelord :GABAA receptor; Radioligand binding assay; GT-002; Triazoloquinazolinedione; Flumazenil; Neuropharmacology;

    Sammanfattning : Gamma-Amino butyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system (CNS) and inhibits the neurotransmission by targeting the ionotropic transmembrane GABAA receptor. Modulators of the GABAA receptor targets the allosteric binding sites and modifies the GABA effect and these sites acts as superior drug targets within psychopharmacology. LÄS MER