Sökning: "co-translational polypeptide processing"

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  1. 1. Single-particle tracking for direct measurements of Trigger Factor ribosome binding in live cells

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Molekylärbiologi

    Författare :Tora Hävermark; [2021]
    Nyckelord :Trigger Factor; Single-particle tracking; in vivo kinetics; co-translational polypeptide processing;

    Sammanfattning : Trigger Factor (TF) is a prokaryotic chaperone protein that exerts its major chaperone activity while associated with translating ribosomes, assisting de novo folding of the emerging nascent chain. Although much is known about the kinetics behind TF-ribosome binding, most results are based on in vitro experiments which fail to mimic the cellular environment. LÄS MER